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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352761
Species: Homo sapiens
RGD Object: Gene
Symbol: RELA
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:17447
Term: geraniol
Definition: A monoterpenoid consisting of two prenyl units linked head-to-tail and functionalised with a hydroxy group at its tail end.
Chemical ID: MESH:C007836
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RELAmultiple interactionsISORela (Mus musculus)6480464CTDgeraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of and results in increased activity of RELA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]PMID:23399806 PMID:26190278 PMID:29050341 PMID:30550845
RELAmultiple interactionsISORela (Rattus norvegicus)6480464CTDgeraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of RELA protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of and affects the localization of RELA protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of RELA protein]PMID:26364502 PMID:28397014 PMID:34343525
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