GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | RELA | affects localization | EXP | | 6480464 | CTD | deoxynivalenol affects the localization of RELA protein | PMID:20347963 | RELA | increases activity | EXP | | 6480464 | CTD | deoxynivalenol results in increased activity of RELA protein | PMID:18599499 | RELA | increases expression | EXP | | 6480464 | CTD | deoxynivalenol results in increased expression of RELA mRNA; deoxynivalenol results in increased expression of RELA protein | PMID:20347963 PMID:22846391 | RELA | multiple interactions | EXP | | 6480464 | CTD | [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; deoxynivalenol promotes the reaction [RELA protein binds to CXCL8 promoter]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased activity of RELA protein]; Lutein inhibits the reaction [deoxynivalenol affects the localization of RELA protein]; Lutein inhibits the reaction [deoxynivalenol results in increased expression of RELA protein]; RELA protein promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased activity of RELA protein] | PMID:17636245 PMID:18599499 PMID:20347963 PMID:22003189 | RELA | increases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | deoxynivalenol results in increased expression of RELA mRNA; deoxynivalenol results in increased expression of RELA protein | PMID:34400200 | RELA | increases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | deoxynivalenol results in increased phosphorylation of RELA protein | PMID:16424113 PMID:24937323 | RELA | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of RELA protein] | PMID:16424113 | | ||||||||||||||||||||||
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