Gene Term Annotation Report - Rat Genome Database

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GENE - TERM ANNOTATION REPORT

RGD ID:	1352672
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	POLR2K
Name:	RNA polymerase II, I and III subunit K

Acc ID:	GO:0005666
Term:	RNA polymerase III complex
Definition:	RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
Definition Source(s):	GOC:krc, GOC:mtg_sensu

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
POLR2K	part_of	IBA	PANTHER:PTN000248542 or PomBase:SPBC19C2.03 or SGD:S000001185	150520179	GO_Central		GO_REF:0000033
POLR2K	part_of	IEA	PANTHER:PTHR12056:SF4 or PANTHER:PTHR12056:SF6	150520179	TreeGrafter		GO_REF:0000118
POLR2K	part_of	IDA		150520179	UniProt	PMID:33335104 PMID:34675218	PMID:33335104 PMID:34675218

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