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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352582
Species: Homo sapiens
RGD Object: Gene
Symbol: IL6
Name: interleukin 6
Acc ID: CHEBI:4466
Term: dexmedetomidine
Definition: A medetomidine that has formula C13H16N2.
Chemical ID: MESH:D020927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL6multiple interactionsISOIl6 (Mus musculus)6480464CTDDexmedetomidine inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]PMID:31954762
IL6multiple interactionsISOIl6 (Rattus norvegicus)6480464CTDDexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Dexmedetomidine promotes the reaction [prolinedithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; prolinedithiocarbamate promotes the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]PMID:29723264
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