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RGD ID: 1352297
Species: Homo sapiens
RGD Object: Gene
Symbol: IGHV4-34
Name: immunoglobulin heavy variable 4-34
Acc ID: GO:0006910
Term: phagocytosis, recognition
Definition: The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Definition Source(s): GOC:curators, ISBN:0781735149
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IGHV4-34 IBAMGI:MGI:96443, MGI:MGI:96445, MGI:MGI:96446, PANTHER:PTN0015109492290271GO_Central (PMID:21873635)

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.