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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352146
Species: Homo sapiens
RGD Object: Gene
Symbol: MT2A
Name: metallothionein 2A
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MT2Aincreases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of MT2A mRNAPMID:21641981 PMID:27017951 PMID:27153756
MT2Amultiple interactionsEXP 6480464CTDgluconic acid inhibits the reaction [Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT2A mRNA]]; Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT2A mRNA]PMID:27017951
MT2Adecreases expressionISOMt2A (Rattus norvegicus)6480464CTDAflatoxin B1 results in decreased expression of MT2 mRNAPMID:14600272
MT2Aincreases expressionISOMt2A (Rattus norvegicus)6480464CTDAflatoxin B1 results in increased expression of MT2A mRNAPMID:15890375 PMID:25378103
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