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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352024
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL10
Name: C-X-C motif chemokine ligand 10
Acc ID: CHEBI:36706
Term: resiquimod
Definition: An imidazoquinoline that has formula C17H22N4O2.
Chemical ID: MESH:C402365
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL10multiple interactionsEXP 6480464CTD[Protein Kinase Inhibitors results in decreased activity of IRAK4 protein] inhibits the reaction [resiquimod promotes the reaction [IRF5 protein binds to CXCL10 promoter]]; resiquimod promotes the reaction [IRF5 protein binds to CXCL10 promoter]; resiquimod promotes the reaction [RELA protein binds to CXCL10 promoter]PMID:28924041
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