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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352024
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL10
Name: C-X-C motif chemokine ligand 10
Acc ID: CHEBI:32234
Term: titanium dioxide
Definition: A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.
Chemical ID: MESH:C009495
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL10increases expressionEXP 6480464CTDtitanium dioxide results in increased expression of CXCL10 mRNAPMID:19695317
CXCL10affects expressionISOCxcl10 (Mus musculus)6480464CTDtitanium dioxide affects the expression of CXCL10 mRNAPMID:29128614
CXCL10decreases expressionISOCxcl10 (Mus musculus)6480464CTDtitanium dioxide results in decreased expression of CXCL10 mRNAPMID:29264374
CXCL10increases expressionISOCxcl10 (Mus musculus)6480464CTDtitanium dioxide results in increased expression of CXCL10 mRNA; titanium dioxide results in increased expression of CXCL10 proteinPMID:21259345 PMID:23557971 PMID:27760801 PMID:28646487
CXCL10increases expressionISOCxcl10 (Rattus norvegicus)6480464CTDtitanium dioxide results in increased expression of CXCL10 mRNAPMID:30012374
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