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RGD ID: 1351452
Species: Homo sapiens
RGD Object: Gene
Symbol: ZPBP
Name: zona pellucida binding protein
Acc ID: GO:0007339
Term: binding of sperm to zona pellucida
Definition: The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
Definition Source(s): GOC:dph, ISBN:0878932437
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:1855701, MGI:MGI:1916626, PANTHER:PTN0003967542290271GO_Central (PMID:21873635)

 IEAInterPro:IPR0108572290271InterPro GO_REF:0000002
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.