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GENE - TERM ANNOTATION REPORT

RGD ID: 1351243
Species: Homo sapiens
RGD Object: Gene
Symbol: TRAF1
Name: TNF receptor associated factor 1
Acc ID: GO:0070534
Term: protein K63-linked ubiquitination
Definition: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
Definition Source(s): GOC:mah, PMID:15556404
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TRAF1involved_inIBAFB:FBgn0265464 or MGI:108072 or PANTHER:PTN000014920 or UniProtKB:Q12933 or UniProtKB:Q9Y4K3150520179GO_Central GO_REF:0000033
TRAF1involved_inIEAPANTHER:PTHR10131:SF96150520179TreeGrafter GO_REF:0000118
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