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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350913
Species: Homo sapiens
RGD Object: Gene
Symbol: BNIP3
Name: BCL2 interacting protein 3
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BNIP3affects expressionEXP 6480464CTDHydrogen Peroxide affects the expression of BNIP3 mRNAPMID:20044591
BNIP3decreases expressionEXP 6480464CTDHydrogen Peroxide results in decreased expression of BNIP3 mRNA; Hydrogen Peroxide results in decreased expression of BNIP3 proteinPMID:12419474 PMID:29061316 PMID:30316844
BNIP3multiple interactionsEXP 6480464CTD[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BNIP3 protein]; BMAL1 protein affects the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased expression of BNIP3 protein]]; BMAL1 protein affects the reaction [Polyphenols inhibits the reaction [Hydrogen Peroxide results in decreased expression of BNIP3 mRNA]]; Polyphenols inhibits the reaction [Hydrogen Peroxide results in decreased expression of BNIP3 mRNA]PMID:29061316 PMID:30316844
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