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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350492
Species: Homo sapiens
RGD Object: Gene
Symbol: CYBB
Name: cytochrome b-245 beta chain
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYBBincreases expressionISOCybb (Rattus norvegicus)6480464CTDThioacetamide results in increased expression of CYBB mRNA; Thioacetamide results in increased expression of CYBB proteinPMID:19822164 PMID:34492290 PMID:34792689
CYBBmultiple interactionsISOCybb (Rattus norvegicus)6480464CTDS100B protein promotes the reaction [Thioacetamide results in increased expression of CYBB protein]; S100B protein promotes the reaction [VEGFA protein promotes the reaction [Thioacetamide results in increased expression of CYBB protein]]; salvianolic acid A inhibits the reaction [Thioacetamide results in increased expression of CYBB protein]; salvianolic acid B inhibits the reaction [Thioacetamide results in increased expression of CYBB protein]; VEGFA protein promotes the reaction [S100B protein promotes the reaction [Thioacetamide results in increased expression of CYBB protein]]; VEGFA protein promotes the reaction [Thioacetamide results in increased expression of CYBB protein]PMID:19822164 PMID:34792689
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