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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350234
Species: Homo sapiens
RGD Object: Gene
Symbol: OSBPL3
Name: oxysterol binding protein like 3
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OSBPL3multiple interactionsEXP 6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of OSBPL3 mRNAPMID:19710929
OSBPL3increases expressionISOOsbpl3 (Mus musculus)6480464CTDpirinixic acid results in increased expression of OSBPL3 mRNAPMID:17950772 PMID:18301758 PMID:20813756
OSBPL3multiple interactionsISOOsbpl3 (Mus musculus)6480464CTDPPARA protein promotes the reaction [pirinixic acid results in increased expression of OSBPL3 mRNA]PMID:17950772
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