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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350002
Species: Homo sapiens
RGD Object: Gene
Symbol: NDUFS1
Name: NADH:ubiquinone oxidoreductase core subunit S1
Acc ID: CHEBI:18243
Term: dopamine
Definition: Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group.
Chemical ID: MESH:D004298
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NDUFS1multiple interactionsISONdufs1 (Mus musculus)6480464CTDNDUFS1 mutant form inhibits the reaction [[EN1 protein co-treated with EN2 protein] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased abundance of Dopamine]]PMID:21892157
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