GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | UGT1A6 | decreases expression | ISO | Ugt1a6 (Rattus norvegicus) | 6480464 | CTD | Diethylnitrosamine results in decreased expression of UGT1A6 mRNA; Diethylnitrosamine results in decreased expression of UGT1A6 protein | PMID:23494807 | UGT1A6 | multiple interactions | ISO | Ugt1a6 (Rattus norvegicus) | 6480464 | CTD | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of UGT1A6 mRNA; [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA; [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA]; allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of UGT1A6 mRNA]; allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of UGT1A6 protein] | PMID:18164116 PMID:18253720 PMID:18544905 PMID:18775883 PMID:22129741 PMID:22467020 PMID:22687989 PMID:23494807 | | ||||||||||||||||||||||
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