Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349475
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1A
Name: heat shock protein family A (Hsp70) member 1A
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Aincreases expressionEXP 6480464CTDAcetaminophen results in increased expression of HSPA1A mRNAPMID:25704631
HSPA1Aaffects expressionISOHspa1a (Mus musculus)6480464CTDAcetaminophen affects the expression of HSPA1A mRNAPMID:17562736
HSPA1Aaffects expressionISOHspa1a (Rattus norvegicus)6480464CTDAcetaminophen affects the expression of HSPA1A mRNAPMID:18246545 PMID:19784758
HSPA1Adecreases expressionISOHspa1a (Rattus norvegicus)6480464CTDAcetaminophen results in decreased expression of HSPA1A mRNAPMID:19784758
HSPA1Aincreases expressionISOHspa1a (Mus musculus)6480464CTDAcetaminophen results in increased expression of HSPA1A mRNA; Acetaminophen results in increased expression of HSPA1A proteinPMID:11743745 PMID:15010265 PMID:29246445
HSPA1Aincreases expressionISOHspa1a (Rattus norvegicus)6480464CTDAcetaminophen results in increased expression of HSPA1A mRNA; Acetaminophen results in increased expression of HSPA1A proteinPMID:15690153 PMID:17202762 PMID:17522070 PMID:18246545 PMID:19784758 PMID:33387578
HSPA1Amultiple interactionsISOHspa1a (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of HSPA1A mRNA; PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of HSPA1A mRNA]; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HSPA1A mRNA]; PTGS2 protein affects the reaction [Acetaminophen results in increased expression of HSPA1A mRNA]PMID:11743745 PMID:17585979 PMID:29246445
Go Back to source page   Continue to Ontology report