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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349475
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1A
Name: heat shock protein family A (Hsp70) member 1A
Acc ID: CHEBI:30512
Term: silver atom
Definition: A copper group element atom that has formula Ag.
Chemical ID: MESH:D012834
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Aincreases expressionEXP 6480464CTDSilver analog results in increased expression of HSPA1A mRNA; Silver results in increased expression of HSPA1A mRNAPMID:17244614 PMID:26014281 PMID:27180073 PMID:27211842 PMID:28959546
HSPA1Amultiple interactionsEXP 6480464CTDSilver promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Silver promotes the reaction [HSF1 protein binds to HSPA1A promoter]PMID:16460681 PMID:17244614
HSPA1Aincreases expressionISOHspa1a (Mus musculus)6480464CTDSilver results in increased expression of HSPA1A mRNAPMID:27131904
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