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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349475
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1A
Name: heat shock protein family A (Hsp70) member 1A
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Aaffects expressionISOHspa1a (Mus musculus)6480464CTDCarbon Tetrachloride affects the expression of HSPA1A mRNAPMID:17484886
HSPA1Adecreases expressionISOHspa1a (Rattus norvegicus)6480464CTDCarbon Tetrachloride results in decreased expression of HSPA1A mRNA; Carbon Tetrachloride results in decreased expression of HSPA1A proteinPMID:12629582 PMID:30723492
HSPA1Aincreases expressionISOHspa1a (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of HSPA1A mRNAPMID:25270620 PMID:27339419 PMID:31919559
HSPA1Aincreases expressionISOHspa1a (Rattus norvegicus)6480464CTDCarbon Tetrachloride results in increased expression of HSPA1A mRNA; Carbon Tetrachloride results in increased expression of HSPA1A proteinPMID:15690153 PMID:16845489 PMID:17522070
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