GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HSPA1A | decreases expression | EXP | | 6480464 | CTD | Formaldehyde results in decreased expression of HSPA1A mRNA; Formaldehyde results in decreased expression of HSPA1A protein | PMID:27664576 PMID:30600586 | HSPA1A | increases expression | EXP | | 6480464 | CTD | Formaldehyde results in increased expression of HSPA1A mRNA | PMID:20655997 PMID:22367790 PMID:23649840 | HSPA1A | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[HSPA1A protein co-treated with Formaldehyde] results in increased phosphorylation of AKT1 protein]; [HSPA1A protein co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Formaldehyde] results in increased expression of GLI2 protein; [HSPA1A protein co-treated with Formaldehyde] results in increased expression of GLI2 protein; [HSPA1A protein co-treated with Formaldehyde] results in increased phosphorylation of AKT1 protein | PMID:30600586 | |
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