GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HSPA1A | decreases expression | EXP | | 6480464 | CTD | Quercetin results in decreased expression of HSPA1A mRNA; Quercetin results in decreased expression of HSPA1A protein | PMID:17234771 PMID:21632981 | HSPA1A | increases expression | EXP | | 6480464 | CTD | Quercetin results in increased expression of HSPA1A protein | PMID:14750173 | HSPA1A | increases response to substance | EXP | | 6480464 | CTD | HSPA1A mutant form results in increased susceptibility to Quercetin | PMID:24126416 | HSPA1A | multiple interactions | EXP | | 6480464 | CTD | [Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPA1A mRNA; HSPA1A mutant form results in increased susceptibility to [Quercetin co-treated with temozolomide] | PMID:17639512 PMID:24126416 | HSPA1A | affects expression | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | Quercetin affects the expression of HSPA1A protein | PMID:14606951 | HSPA1A | decreases expression | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | Quercetin results in decreased expression of HSPA1A mRNA | PMID:17349211 | HSPA1A | multiple interactions | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | Quercetin inhibits the reaction [Hydrogen Peroxide affects the localization of HSPA1A protein]; Quercetin inhibits the reaction [Hydrogen Peroxide promotes the reaction [HSPA1A protein binds to HMGB1 protein]]; Quercetin inhibits the reaction [sodium arsenite results in increased expression of HSPA1A protein] | PMID:14606951 PMID:17513788 | |
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