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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348698
Species: Homo sapiens
RGD Object: Gene
Symbol: NCF1
Name: neutrophil cytosolic factor 1
Acc ID: CHEBI:125619
Term: N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide
Definition: A piperazine that has formula C25H34N4O2.
Chemical ID: MESH:C090413
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NCF1multiple interactionsISONcf1 (Mus musculus)6480464CTDN-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased phosphorylation of and affects the localization of NCF1 protein]PMID:30366073
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