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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348590
Species: Homo sapiens
RGD Object: Gene
Symbol: CGA
Name: glycoprotein hormones, alpha polypeptide
Acc ID: CHEBI:30772
Term: butyric acid
Definition: A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Chemical ID: MESH:D020148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CGAdecreases stabilityEXP 6480464CTDButyric Acid results in decreased stability of CGA mRNAPMID:1693837
CGAincreases expressionEXP 6480464CTDButyric Acid results in increased expression of CGA mRNA; Butyric Acid results in increased expression of CGA proteinPMID:1693836 PMID:1693837
CGAmultiple interactionsEXP 6480464CTD[Theophylline co-treated with Butyric Acid] results in increased expression of CGA mRNA; Theophylline inhibits the reaction [Butyric Acid results in decreased stability of CGA mRNA]; Theophylline promotes the reaction [Butyric Acid results in increased expression of CGA protein]PMID:1693836 PMID:1693837
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