GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ACTA2 | increases expression | ISO | Acta2 (Mus musculus) | 6480464 | CTD | Hydrogen Peroxide results in increased expression of ACTA2 protein | PMID:32659284 | ACTA2 | increases expression | ISO | Acta2 (Rattus norvegicus) | 6480464 | CTD | Hydrogen Peroxide results in increased expression of ACTA2 mRNA; Hydrogen Peroxide results in increased expression of ACTA2 protein | PMID:16284289 PMID:23022513 | ACTA2 | multiple interactions | ISO | Acta2 (Mus musculus) | 6480464 | CTD | 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein]; 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein]; CAT protein inhibits the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein]; SHC1 protein promotes the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein] | PMID:32659284 | ACTA2 | multiple interactions | ISO | Acta2 (Rattus norvegicus) | 6480464 | CTD | Progesterone promotes the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein]; tetramethylpyrazine inhibits the reaction [Hydrogen Peroxide results in increased expression of ACTA2 mRNA] | PMID:16284289 PMID:23022513 | | ||||||||||||||||||||||
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