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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348108
Species: Homo sapiens
RGD Object: Gene
Symbol: CAVIN2
Name: caveolae associated protein 2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CAVIN2affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of CAVIN2 exonPMID:27901495
CAVIN2increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of CAVIN2 mRNAPMID:20106945 PMID:21632981 PMID:21871943 PMID:22316170 PMID:26238291 PMID:32234424
CAVIN2increases methylationEXP 6480464CTDBenzo(a)pyrene results in increased methylation of CAVIN2 promoterPMID:27901495
CAVIN2affects expressionISOCavin2 (Mus musculus)6480464CTDBenzo(a)pyrene affects the expression of CAVIN2 mRNAPMID:22342234
CAVIN2decreases expressionISOCavin2 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of CAVIN2 mRNAPMID:19770486
CAVIN2increases expressionISOCavin2 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of CAVIN2 mRNAPMID:32417428
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