GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CASP12 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP12 protein] | PMID:37300854 | CASP12 | multiple interactions | ISO | Casp12 (Rattus norvegicus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP12 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP12 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] | PMID:18077580 PMID:21145380 PMID:28296042 | CASP12 | multiple interactions | ISO | Casp12 (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of and results in increased activity of CASP12 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of CASP12 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP12 protein]] | PMID:21616140 PMID:25451595 PMID:31330229 | | ||||||||||||||||||||||
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