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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347335
Species: Homo sapiens
RGD Object: Gene
Symbol: HSP90AA1
Name: heat shock protein 90 alpha family class A member 1
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSP90AA1affects bindingEXP 6480464CTDHSP90AA1 protein binds to CopperPMID:15359738
HSP90AA1multiple interactionsEXP 6480464CTD[Chelating Agents binds to Copper] which results in decreased expression of HSP90AA1 mRNA; [Disulfiram binds to Copper] which results in decreased expression of HSP90AA1 mRNA; [Organoselenium Compounds binds to Copper] which results in decreased expression of HSP90AA1 protein; [Organoselenium Compounds binds to Copper] which results in increased expression of HSP90AA1 mRNAPMID:24690739 PMID:25167922 PMID:30911355
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