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GENE - TERM ANNOTATION REPORT

RGD ID: 1346700
Species: Homo sapiens
RGD Object: Gene
Symbol: SUFU
Name: SUFU negative regulator of hedgehog signaling
Acc ID: GO:0005634
Term: nucleus
Definition: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SUFUlocated_inIEAUniProtKB:Q9Z0P7 or ensembl:ENSMUSP00000107498150520179Ensembl GO_REF:0000107
SUFUis_active_inIBAFB:FBgn0005355 or MGI:1345643 or PANTHER:PTN000859153 or UniProtKB:Q9UMX1150520179GO_Central GO_REF:0000033
SUFUlocated_inIEAPANTHER:PTHR10928:SF2150520179TreeGrafter GO_REF:0000118
SUFUlocated_inIDA 150520179UniProt PMID:10806483

PMID:10806483
SUFUlocated_inIEAUniProtKB-KW:KW-0539150520179UniProt GO_REF:0000043
SUFUlocated_inIEAUniProtKB-SubCell:SL-0191150520179UniProt GO_REF:0000044
SUFUlocated_inIMP 150520179UniProt PMID:28965847

PMID:28965847
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