Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346388
Species: Homo sapiens
RGD Object: Gene
Symbol: SUMO3
Name: small ubiquitin like modifier 3
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SUMO3decreases expressionEXP 6480464CTDtrichostatin A results in decreased expression of SUMO3 mRNAPMID:24935251 PMID:26272509
SUMO3multiple interactionsEXP 6480464CTD[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SUMO3 mRNA; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]; trichostatin A promotes the reaction [[PIAS1 protein co-treated with SUMO3 protein] results in increased sumoylation of NR1I2 protein]PMID:26883953 PMID:27188386
Go Back to source page   Continue to Ontology report