GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | FAS | affects localization | EXP | | 6480464 | CTD | resveratrol affects the localization of FAS protein | PMID:12902349 | FAS | increases expression | EXP | | 6480464 | CTD | resveratrol analog results in increased expression of FAS mRNA; resveratrol results in increased expression of FAS mRNA; resveratrol results in increased expression of FAS protein | PMID:17261084 PMID:19846903 PMID:24044363 PMID:26341291 | FAS | increases response to substance | EXP | | 6480464 | CTD | FAS protein results in increased susceptibility to resveratrol; resveratrol results in increased susceptibility to FAS protein | PMID:19561642 PMID:20097879 | FAS | multiple interactions | EXP | | 6480464 | CTD | [allyl sulfide co-treated with Resveratrol] results in increased expression of FAS protein; [IFNG protein results in increased expression of and results in increased localization of FAS protein] which results in increased susceptibility to Resveratrol; Capsaicin promotes the reaction [Resveratrol results in increased expression of FAS protein]; Nystatin inhibits the reaction [Resveratrol affects the localization of FAS protein]; Resveratrol promotes the reaction [FAS protein binds to CASP10 protein]; Resveratrol promotes the reaction [FAS protein binds to CASP8 protein]; Resveratrol promotes the reaction [FAS protein binds to FADD protein] | PMID:12902349 PMID:18512326 PMID:19561642 PMID:19846903 | FAS | increases expression | ISO | Fas (Mus musculus) | 6480464 | CTD | resveratrol results in increased expression of FAS mRNA; resveratrol results in increased expression of FAS protein | PMID:17872969 PMID:22610192 | FAS | increases expression | ISO | Fas (Rattus norvegicus) | 6480464 | CTD | resveratrol results in increased expression of FAS mRNA | PMID:20797428 | FAS | multiple interactions | ISO | Fas (Rattus norvegicus) | 6480464 | CTD | resveratrol inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in decreased expression of FAS mRNA]; resveratrol inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in decreased expression of FAS protein] | PMID:23127599 | | ||||||||||||||||||||||
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