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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346236
Species: Homo sapiens
RGD Object: Gene
Symbol: TAAR1
Name: trace amine associated receptor 1
Acc ID: CHEBI:44715
Term: (R)-octopamine
Definition: An octopamine that has formula 153.17848.
Chemical ID: MESH:D009655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TAAR1increases activityEXP 6480464CTDOctopamine results in increased activity of TAAR1 proteinPMID:19725810
TAAR1multiple interactionsEXP 6480464CTD[Octopamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A2 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A4 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; Methylphenidate inhibits the reaction [SLC6A3 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; SLC6A2 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]; SLC6A3 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]; SLC6A4 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]PMID:17234900 PMID:19725810
TAAR1increases activityISOTaar1 (Mus musculus)6480464CTDOctopamine results in increased activity of TAAR1 proteinPMID:19725810
TAAR1multiple interactionsISOTaar1 (Mus musculus)6480464CTD[Octopamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMPPMID:19725810
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