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GENE - TERM ANNOTATION REPORT

RGD ID: 1346006
Species: Homo sapiens
RGD Object: Gene
Symbol: UBE2A
Name: ubiquitin conjugating enzyme E2 A
Acc ID: GO:0033503
Term: HULC complex
Definition: A ubiquitin ligase complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp6, Shf1, Brl2/Rfp1 and Brl1/Rfp2.
Definition Source(s): GOC:mah, PMID:17363370, PMID:17374714
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UBE2Apart_ofIBAPANTHER:PTN000630652 or PomBase:SPAC18B11.07c or UniProtKB:P49459 or UniProtKB:P63146150520179GO_Central GO_REF:0000033
UBE2Apart_ofIEAPANTHER:PTHR24067:SF243 or PANTHER:PTHR24067:SF254150520179TreeGrafter GO_REF:0000118
UBE2Apart_ofIDA 150520179UniProt PMID:19410543

PMID:19410543
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