GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PARP1 | increases cleavage | EXP | | 6480464 | CTD | Chlorpyrifos results in increased cleavage of PARP1 protein | PMID:24793810 | PARP1 | increases expression | EXP | | 6480464 | CTD | Chlorpyrifos results in increased expression of PARP1 mRNA; Chlorpyrifos results in increased expression of PARP1 protein; Chlorpyrifos results in increased expression of PARP1 protein modified form | PMID:23416140 PMID:28887667 | PARP1 | increases cleavage | ISO | Parp1 (Mus musculus) | 6480464 | CTD | Chlorpyrifos results in increased cleavage of PARP1 protein | PMID:34289071 PMID:36252918 | PARP1 | increases cleavage | ISO | Parp1 (Rattus norvegicus) | 6480464 | CTD | Chlorpyrifos results in increased cleavage of PARP1 protein | PMID:22714038 PMID:29859868 | PARP1 | increases expression | ISO | Parp1 (Rattus norvegicus) | 6480464 | CTD | Chlorpyrifos results in increased expression of PARP1 mRNA; Chlorpyrifos results in increased expression of PARP1 protein | PMID:33908150 | PARP1 | multiple interactions | ISO | Parp1 (Rattus norvegicus) | 6480464 | CTD | [Hesperidin co-treated with Chlorpyrifos] results in increased expression of PARP1 mRNA; [Hesperidin co-treated with Chlorpyrifos] results in increased expression of PARP1 protein; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased cleavage of PARP1 protein]; STAT1 protein affects the reaction [Chlorpyrifos results in increased cleavage of PARP1 protein] | PMID:22714038 PMID:29859868 PMID:33908150 | |
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