GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP2E1 | decreases activity | EXP | | 6480464 | CTD | S-Adenosylmethionine results in decreased activity of CYP2E1 protein | PMID:15763544 | CYP2E1 | decreases activity | ISO | Cyp2e1 (Rattus norvegicus) | 6480464 | CTD | S-Adenosylmethionine results in decreased activity of CYP2E1 protein | PMID:15763544 | CYP2E1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased expression of CYP2E1 protein]; S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein] | PMID:15983038 PMID:22683606 | CYP2E1 | multiple interactions | ISO | Cyp2e1 (Rattus norvegicus) | 6480464 | CTD | S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]; S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Ethanol] | PMID:15763544 | |
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