GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP2E1 | affects expression | ISO | Cyp2e1 (Rattus norvegicus) | 6480464 | CTD | resveratrol affects the expression of CYP2E1 mRNA | PMID:15748624 | CYP2E1 | decreases activity | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | resveratrol analog results in decreased activity of CYP2E1 protein; resveratrol results in decreased activity of CYP2E1 protein | PMID:16684708 PMID:18420780 PMID:25956474 PMID:27174446 | CYP2E1 | increases expression | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | resveratrol results in increased expression of CYP2E1 mRNA | PMID:22610192 | CYP2E1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | Resveratrol inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]; Resveratrol inhibits the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; Resveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP2E1 protein]; Resveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP2E1 mRNA] | PMID:18789925 PMID:23202692 PMID:25956474 | |
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