GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP2E1 | increases chemical synthesis | EXP | | 6480464 | CTD | CYP2E1 protein results in increased chemical synthesis of Reactive Oxygen Species | PMID:10498651 | CYP2E1 | multiple interactions | EXP | | 6480464 | CTD | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species; [Ethanol co-treated with CYP2E1 protein] results in increased abundance of Reactive Oxygen Species; Fomepizole inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species] | PMID:18845238 PMID:22222162 | CYP2E1 | affects chemical synthesis | ISO | Cyp2e1 (Rattus norvegicus) | 6480464 | CTD | CYP2E1 protein affects the chemical synthesis of Reactive Oxygen Species | PMID:14693714 | CYP2E1 | decreases response to substance | ISO | Cyp2e1 (Rattus norvegicus) | 6480464 | CTD | CYP2E1 protein results in decreased susceptibility to Reactive Oxygen Species | PMID:12470497 | CYP2E1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | [CYP2E1 protein results in increased hydroxylation of 4-biphenylamine] which results in increased abundance of Reactive Oxygen Species | PMID:25601990 | | ||||||||||||||||||||||
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