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GENE - TERM ANNOTATION REPORT

RGD ID: 1344695
Species: Homo sapiens
RGD Object: Gene
Symbol: SOX2
Name: SRY-box transcription factor 2
Acc ID: GO:0005634
Term: nucleus
Definition: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOX2located_inIEAUniProtKB:D4A543 or ensembl:ENSRNOP00000016236150520179Ensembl GO_REF:0000107
SOX2is_active_inIBAFB:FBgn0000411 or FB:FBgn0005612 or FB:FBgn0005613 or FB:FBgn0029123 or FB:FBgn0036411 or MGI:103559 or MGI:107543 or MGI:98357 or MGI:98359 or MGI:98363 or MGI:98364 or MGI:98366 or MGI:98369 or MGI:98660 or PANTHER:PTN000030384 or PomBase:SPBC23G7.09 or Sox17 (Rattus norvegicus) or Sox2 (Rattus norvegicus) or Sox11 (Rattus norvegicus) or UniProtKB:O15370 or UniProtKB:P35713 or UniProtKB:P35716 or UniProtKB:P41225 or UniProtKB:P48430 or UniProtKB:P48431 or UniProtKB:Q05066 or UniProtKB:Q06945 or UniProtKB:Q9BT81 or UniProtKB:Q9H6I2 or WB:WBGene00004771150520179GO_Central GO_REF:0000033
SOX2located_inICGO:0003677150520179HGNC-UCL PMID:16153702

PMID:16153702
SOX2located_inIDA 150520179UniProt PMID:17291498 PMID:18027866 PMID:18285410

PMID:17291498 PMID:18027866 PMID:18285410
SOX2located_inIEAUniProtKB-KW:KW-0539150520179UniProt GO_REF:0000043
SOX2located_inIEAUniProtKB-SubCell:SL-0191150520179UniProt GO_REF:0000044
SOX2located_inIEAUniRule:UR000400811150520179UniProt GO_REF:0000104
SOX2located_inNAS 150520179UniProt PMID:7849401

PMID:7849401
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