GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL1RN | multiple interactions | EXP | | 6480464 | CTD | [Ozone results in increased abundance of Soot metabolite] which results in increased expression of IL1RN mRNA | PMID:28410501 | IL1RN | increases expression | ISO | Il1rn (Mus musculus) | 6480464 | CTD | Ozone results in increased expression of IL1RN mRNA | PMID:25658374 PMID:33026818 | IL1RN | multiple interactions | ISO | Il1rn (Mus musculus) | 6480464 | CTD | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of IL1RN mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL1RN mRNA; ADIPOQ protein inhibits the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL1RN protein]; IL1RN protein inhibits the reaction [Ozone results in increased expression of CXCL1 protein]; IL1RN protein inhibits the reaction [Ozone results in increased expression of CXCL2 protein]; IL1RN protein inhibits the reaction [Ozone results in increased expression of TNF protein]; IL1RN protein results in decreased susceptibility to [Ozone co-treated with Methacholine Chloride] | PMID:14754758 PMID:22474022 PMID:27106289 PMID:34911549 | |
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