GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNF | increases expression | EXP | | 6480464 | CTD | Chromium results in increased expression of TNF mRNA | PMID:15878362 | TNF | multiple interactions | EXP | | 6480464 | CTD | Chromium inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Chromium promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Chromium results in increased expression of and results in increased secretion of TNF protein; herbimycin inhibits the reaction [Chromium results in increased expression of TNF mRNA] | PMID:10593907 PMID:15878362 PMID:7864660 PMID:8968517 | TNF | increases expression | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | Chromium deficiency results in increased expression of TNF protein | PMID:19846803 | TNF | increases secretion | ISO | Tnf (Mus musculus) | 6480464 | CTD | Chromium results in increased secretion of TNF protein | PMID:12423593 | TNF | multiple interactions | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein] | PMID:15862027 | | ||||||||||||||||||||||
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