GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NR1I3 | decreases activity | EXP | | 6480464 | CTD | pirinixic acid results in decreased activity of NR1I3 protein | PMID:17962186 | NR1I3 | multiple interactions | EXP | | 6480464 | CTD | pirinixic acid inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein] | PMID:17962186 | NR1I3 | affects expression | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | pirinixic acid affects the expression of NR1I3 mRNA | PMID:25949234 | NR1I3 | affects expression | ISO | Nr1i3 (Rattus norvegicus) | 6480464 | CTD | pirinixic acid affects the expression of NR1I3 mRNA | PMID:19483382 | NR1I3 | affects localization | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | pirinixic acid affects the localization of NR1I3 protein | PMID:17962186 | NR1I3 | increases activity | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | pirinixic acid results in increased activity of NR1I3 protein | PMID:30203046 | NR1I3 | increases expression | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | pirinixic acid results in increased expression of NR1I3 mRNA | PMID:17426115 | NR1I3 | increases expression | ISO | Nr1i3 (Rattus norvegicus) | 6480464 | CTD | pirinixic acid results in increased expression of NR1I3 mRNA; pirinixic acid results in increased expression of NR1I3 protein | PMID:18023279 PMID:19631232 PMID:20208394 PMID:32741897 | NR1I3 | multiple interactions | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | MED1 protein promotes the reaction [pirinixic acid affects the localization of NR1I3 protein]; pirinixic acid inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [NR1I3 protein binds to CYP2B10 promoter]] | PMID:17962186 | NR1I3 | multiple interactions | ISO | Nr1i3 (Rattus norvegicus) | 6480464 | CTD | Phenobarbital promotes the reaction [pirinixic acid results in increased expression of NR1I3 mRNA]; pirinixic acid promotes the reaction [Phenobarbital results in increased expression of NR1I3 mRNA] | PMID:18023279 PMID:19631232 | |
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