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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344001
Species: Homo sapiens
RGD Object: Gene
Symbol: GDF15
Name: growth differentiation factor 15
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GDF15affects expressionEXP 6480464CTDAflatoxin B1 affects the expression of GDF15 proteinPMID:20106945
GDF15increases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of GDF15 mRNAPMID:21632981 PMID:21641981 PMID:22100608 PMID:27153756 PMID:32234424 PMID:35690182
GDF15increases expressionISOGdf15 (Rattus norvegicus)6480464CTDAflatoxin B1 results in increased expression of GDF15 mRNAPMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 PMID:23630614 PMID:33354967
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