GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | RASSF1 | decreases methylation | EXP | | 6480464 | CTD | Arsenic Trioxide results in decreased methylation of RASSF1 gene; Arsenic Trioxide results in decreased methylation of RASSF1 promoter | PMID:16613325 PMID:20079060 | RASSF1 | increases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in increased expression of RASSF1 mRNA; Arsenic Trioxide results in increased expression of RASSF1 protein | PMID:16613325 PMID:20079060 | RASSF1 | multiple interactions | EXP | | 6480464 | CTD | [Arsenic Trioxide results in decreased methylation of RASSF1 promoter] which results in increased expression of RASSF1 mRNA; Arsenic Trioxide promotes the reaction [Decitabine results in increased expression of RASSF1 mRNA]; Arsenic Trioxide results in increased expression of and affects the localization of RASSF1 protein; Decitabine promotes the reaction [Arsenic Trioxide results in increased expression of RASSF1 mRNA] | PMID:16613325 | |
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