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GENE - TERM ANNOTATION REPORT

RGD ID: 1343662
Species: Homo sapiens
RGD Object: Gene
Symbol: DNASE2
Name: deoxyribonuclease 2, lysosomal
Acc ID: GO:0006309
Term: apoptotic DNA fragmentation
Definition: The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.
Definition Source(s): GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976, PMID:15723341, PMID:23379520
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DNASE2involved_inIBAPANTHER:PTN000092274 or WB:WBGene00000799 or WB:WBGene00003828 or WB:WBGene00007056150520179GO_Central GO_REF:0000033
DNASE2involved_inIEAPANTHER:PTHR10858:SF9150520179TreeGrafter GO_REF:0000118
DNASE2involved_inIEAUniRule:UR001903773150520179UniProt GO_REF:0000104
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