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GENE - TERM ANNOTATION REPORT

RGD ID: 1343412
Species: Homo sapiens
RGD Object: Gene
Symbol: HUWE1
Name: HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
Acc ID: GO:0005634
Term: nucleus
Definition: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HUWE1located_inIEAUniProtKB:P51593 or ensembl:ENSRNOP00000095129150520179Ensembl GO_REF:0000107
HUWE1is_active_inIBAFB:FBgn0030674 or PANTHER:PTN000135257 or UniProtKB:Q7Z6Z7 or UniProtKB:Q8IYU2150520179GO_Central GO_REF:0000033
HUWE1located_inIEAPANTHER:PTHR11254:SF67150520179TreeGrafter GO_REF:0000118
HUWE1located_inIEAUniProtKB-KW:KW-0539150520179UniProt GO_REF:0000043
HUWE1located_inIEAUniProtKB-SubCell:SL-0191150520179UniProt GO_REF:0000044
HUWE1located_inISSUniProtKB:P51593150520179UniProt GO_REF:0000024
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