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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1342708
Species: Homo sapiens
RGD Object: Gene
Symbol: UGT1A8
Name: UDP glucuronosyltransferase family 1 member A8
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UGT1A8increases glucuronidationEXP 6480464CTDUGT1A8 protein results in increased glucuronidation of Estradiol; UGT1A8 protein results in increased glucuronidation of Estradiol analogPMID:15117964 PMID:15472229 PMID:17898154
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