GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PPARGC1A | decreases expression | ISO | Ppargc1a (Mus musculus) | 6480464 | CTD | triptolide results in decreased expression of PPARGC1A mRNA | PMID:32835833 | PPARGC1A | multiple interactions | ISO | Ppargc1a (Mus musculus) | 6480464 | CTD | resveratrol inhibits the reaction [triptolide affects the localization of and results in increased acetylation of PPARGC1A protein]; triptolide affects the localization of and results in increased acetylation of PPARGC1A protein; triptolide results in decreased expression of and results in decreased activity of PPARGC1A protein | PMID:29723566 | PPARGC1A | multiple interactions | ISO | Ppargc1a (Rattus norvegicus) | 6480464 | CTD | 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in increased acetylation of and affects the localization of PPARGC1A protein]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in increased acetylation of PPARGC1A protein]]; triptolide results in increased acetylation of and affects the localization of PPARGC1A protein | PMID:36436616 | | ||||||||||||||||||||||
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