GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SLC22A2 | affects transport | EXP | | 6480464 | CTD | SLC22A2 protein affects the transport of Tetraethylammonium | PMID:15496291 PMID:16141367 | SLC22A2 | decreases uptake | EXP | | 6480464 | CTD | SLC22A2 gene polymorphism results in decreased uptake of Tetraethylammonium | PMID:17220237 | SLC22A2 | increases import | EXP | | 6480464 | CTD | SLC22A2 protein results in increased import of Tetraethylammonium; SLC22A2 results in increased import of Tetraethylammonium | PMID:28629854 PMID:30189235 PMID:9260930 | SLC22A2 | increases uptake | EXP | | 6480464 | CTD | SLC22A2 protein results in increased uptake of Tetraethylammonium | PMID:16006492 PMID:17220237 PMID:21256917 PMID:23770354 PMID:27989701 | SLC22A2 | multiple interactions | EXP | | 6480464 | CTD | 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole inhibits the reaction [SLC22A2 protein results in increased import of Tetraethylammonium]; 3-amino-1-methyl-5H-pyrido(4,3-b)indole inhibits the reaction [SLC22A2 protein results in increased import of Tetraethylammonium]; [Mercuric Chloride results in decreased activity of SLC22A2 protein] which results in decreased uptake of Tetraethylammonium; Aconitine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Amitriptyline inhibits the reaction [SLC22A2 protein results in increased import of Tetraethylammonium]; Amitriptyline inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; bisphenol F promotes the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; bisphenol S promotes the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Chlorpyrifos inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Cimetidine inhibits the reaction [SLC22A2 protein affects the transport of Tetraethylammonium]; Famotidine inhibits the reaction [SLC22A2 protein affects the transport of Tetraethylammonium]; Fenitrothion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Haloperidol inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Lidocaine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Malathion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Mianserin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Nicotine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; tetrabromobisphenol A inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Tetraethylammonium inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Tetraethylammonium inhibits the reaction [SLC22A2 protein results in increased uptake of Ethidium]; Tobacco Smoke Pollution inhibits the reaction [SLC22A2 protein results in increased import of Tetraethylammonium]; Triazolam inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] | PMID:15496291 PMID:16141367 PMID:17287197 PMID:19357179 PMID:23770354 PMID:27989701 PMID:28629854 PMID:30189235 PMID:32003934 | SLC22A2 | increases uptake | ISO | Slc22a2 (Rattus norvegicus) | 6480464 | CTD | SLC22A2 protein results in increased uptake of Tetraethylammonium | PMID:12440152 PMID:16006492 PMID:9830022 | SLC22A2 | multiple interactions | ISO | Slc22a2 (Rattus norvegicus) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Chlorpheniramine affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Corticosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Desoxycorticosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Disopyramide affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Dopamine affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Estradiol affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Progesterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Testosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] | PMID:12440152 PMID:9830022 | | ||||||||||||||||||||||
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