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GENE - TERM ANNOTATION REPORT

RGD ID: 1342514
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL13
Name: C-X-C motif chemokine ligand 13
Acc ID: GO:0008009
Term: chemokine activity
Definition: The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
Definition Source(s): GOC:BHF, GOC:rl, PMID:12183377, Wikipedia:Chemokine
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL13enablesIDA 150520179BHF-UCL PMID:11554781

PMID:11554781
CXCL13enablesIBAMGI:1339941 or MGI:1888499 or MGI:1888712 or MGI:3037818 or PANTHER:PTN000021269 or Cxcl1 (Rattus norvegicus) or Cxcl10 (Rattus norvegicus) or Cxcl3 (Rattus norvegicus) or Cxcl2 (Rattus norvegicus) or Cxcl6 (Rattus norvegicus) or Cxcl11 (Rattus norvegicus) or UniProtKB:A0A0G2KYH9 or UniProtKB:O14625 or UniProtKB:O43927 or UniProtKB:P02778 or UniProtKB:P10145 or UniProtKB:P80162 or UniProtKB:P80221 or UniProtKB:Q07325 or ZFIN:ZDB-GENE-090313-165150520179GO_Central GO_REF:0000033
CXCL13enablesIEAInterPro:IPR001089 or InterPro:IPR001811 or InterPro:IPR018048 or InterPro:IPR033899 or InterPro:IPR036048 or InterPro:IPR039809150520179InterPro GO_REF:0000002
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