GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Xbp1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of XBP1 protein alternative form]]; 4-phenylbutyric acid affects the reaction [LEPR gene mutant form affects the splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased splicing of XBP1 mRNA] | PMID:23274897 PMID:27578021 PMID:30602124 PMID:31298478 PMID:33771661 PMID:35413383 PMID:37692514 | Xbp1 | decreases expression | ISO | XBP1 (Homo sapiens) | 6480464 | CTD | 4-phenylbutyric acid results in decreased expression of XBP1 protein alternative form | PMID:29444456 PMID:30796460 | Xbp1 | multiple interactions | ISO | Xbp1 (Rattus norvegicus) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of XBP1 protein alternative form] | PMID:20165829 PMID:33651226 PMID:34214594 | Xbp1 | multiple interactions | ISO | XBP1 (Homo sapiens) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [[Amiodarone results in increased splicing of XBP1 mRNA] which results in increased expression of XBP1 mRNA alternative form]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [bisphenol A results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased expression of XBP1 protein alternative form] | PMID:20165829 PMID:25295624 PMID:27638906 PMID:28245985 PMID:29444456 PMID:30796460 PMID:36670177 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |