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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1331978
Species: Mus musculus
RGD Object: Gene
Symbol: Ppargc1b
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 beta
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1bmultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of PPARGC1B mRNAPMID:28433925
Ppargc1bincreases expressionISOPpargc1b (Rattus norvegicus)6480464CTDDiethylhexyl Phthalate results in increased expression of PPARGC1B mRNAPMID:22672789
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