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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1331975
Species: Mus musculus
RGD Object: Gene
Symbol: Pomc
Name: pro-opiomelanocortin-alpha
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pomcmultiple interactionsEXP 6480464CTDPOMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of ICAM1 mRNA]; POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]; POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]; POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP2 mRNA]; POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of VCAM1 mRNA]; POMC protein promotes the reaction [Carbon Tetrachloride results in increased activity of MMP2 protein]; POMC protein promotes the reaction [Carbon Tetrachloride results in increased expression of MMP1 protein]PMID:16508911
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